It was developed through selective breeding - two specimens of Japanese brown frog (Rana japonica) that had a genetic mutation giving them pale skin were bred, then their offspring were selectively bred to focus on the transprarency. The frog is something of a rarity - most of the world’s known transparent creatures live underwater, and few are four-legged animals.
Professor Sumida says, "Transparent frogs will prove useful as laboratory animals because they make it easier and cheaper to observe the development and progress of cancer, the growth and aging of internal organs, and the effects of chemicals on organs."
Source - Fortean Times
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